Medical Microdevices

Research : Smart Devices : Discrete Devices : Medical Microdevices

In vivo imaging probe.

Implantable GERD sensor on a flexible substrate.

An integrated pain management system.

Objective:

Research and development of miniature cost-effective microdevices including sensors and actuators for medical applications targeting implants, in vivo and ex vivo diagnosis and surgical instrumentations.

Approach:

Batch fabrication and manufacturing processes to ensure cost effectiveness and miniaturization.
Application and problem-oriented approaches to address needs in medical applications.
Target the whole systems in solving medical issue and addressing patient’s needs and surgical/treatment procedures.
System configurations include telemetry, micropumps, chemical sensors, physical sensors, electrodes, optical interrogation, magnetic interrogation, fiber optics, MEMS sensors and actuators, microrobotics and control mechanism.

Accomplishments:

Demonstration of in vivo near infrared fiber optics scanning probes for brain tissue imaging, artery imaging, skin cancer early detection, active endoscopy and retinal detachment and retinoschisis diagnosis.
Demonstration of miniature impedance and pH sensors for GERD (gastroesophageal reflux disease) monitoring.
Demonstration of sensors on flexible substrates for implants.
Micropackaging and demonstration of safe implantable drug delivery systems.
Demonstration of wireless chemical and physical sensors. Applications include prevention of sudden infant death syndrome (SIDS) and for senior/patient homecare.
Demonstration of integrated pain management by neurostimulation.
Design and demonstration of integrated bandages for wound healing.

Publications:

[1]	“A Compact Optical Fiber Scanner for Medical Imaging,” Naresh Dhaubanjar, Hans Hu, Digent Dave, Pratibha Phuyal, Jeongsik Sin, Harry Stephanou and J.-C. Chiao¬, SPIE International Smart Materials, Nano- & Micro-Smart Systems Symposium, Adelaide, Australia, Dec.10-13 2006.
[2]	“A Wireless Sensor for Detecting Gastroesophageal Reflux,” Thermpon Ativanichayaphong, Wen-Ding Huang, Jianqun Wang, Smitha M.N. Rao, H.F. Tibbals, Shou-Jiang Tang, Stuart Spechler, Harry Stephanou and J.-C. Chiao, SPIE International Smart Materials, Nano- & Micro-Smart Systems Symposium, Adelaide, Australia, Dec.10-13 2006.
[3]	“Progress in the Development of the MEMS Based In-plane Micropump: Experimental Motion Characterization,” Smitha M.N. Rao, Saket Karajgikar, Jeongsik Sin, Dan Popa, Harry Stephanou, J.-C. Chiao, TEXMEMS, The VIII International Conference on Micro Electro Mechanical Systems, Oct. 9 2006.
[4]	“Development Of Integrative Wireless Sensor And Stimulator For Modulating Neuronal Activities,” T. Ativanichayaphong, J. He, Y.B. Peng, H. Stephanou and J.-C. Chiao, The 36th Annual Meeting, Society for Neuroscience, Neuroscience 2006, Atlanta, Georgia, Oct. 14-18 2006.
[5]	“An Optical Scanner Based on Electromagnetically Actuated Optical Fiber,” Hans Hu, Kevin Le, and J.-C. Chiao, Photonics West Symposium, Micromachining and Microfabrication Process Technology Conference, San Jose, Jan. 21-26, 2006.
[6]	“A compact fiber optic scanner using electromagnetic actuation,” Hans Hu, Kevin Le and J.C. Chiao, Microelectronics, MEMS, and Nanotechnology Symposium, Photonics: Design, Technology, and Packaging Conference, Brisbane Australia, Dec. 11-14, 2005.
[7]	“MEMS-based Implantable Drug Delivery System,” Smitha M. N. Rao, Amit Mhatre, Dan O. Popa, J. -C. Chiao, Thermpon Ativanichayaphong, Jeongsik Sin, and Harry E. Stephanou, 2005 TexMEMS, The VII International Conference on Micro Electro Mechanical Systems, El Paso, TX, USA and Ciudad Juárez, Mexico. Sept. 21-22, 2005.
[8]	“Modeling and Design of a Fiber Optic Pressure Sensor,” Shruthika Prasanna, Smitha Malalur Nagaraja, Praveen Pandojirao-Sunkojirao and J.-C. Chiao, 2005 TexMEMS, The VII International Conference on Micro Electro Mechanical Systems, El Paso, TX, USA and Ciudad Juárez, Mexico. Sept. 21-22, 2005.
[9]	“A Miniature Optical Pressure Sensor, ” Smitha M.N.Rao, Praveen Pandojirao-Sunkojirao, Shruthika Prasanna and J.-C. Chiao, 2005 TexMEMS, The VII International Conference on Micro Electro Mechanical Systems, El Paso, TX, USA and Ciudad Juárez, Mexico. Sept. 21-22, 2005.